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Small Mammals + English

  • There are four major hormonal diseases in ferrets. This handout covers adrenal gland disease and diabetes mellitus. Adrenal gland disease occurs in a large number of ferrets in North America, while diabetes mellitus is a rare, but important problem.

  • Insulin glargine is an injectable medication used in cats, dogs, ferrets, guinea pigs, and horses with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsive).

  • Insulin is injected under the skin to treat diabetes, ketoacidosis, and high potassium levels. Side effects may include low or high blood sugar levels, insulin resistance, and skin allergic reactions to the injections. Do not use in pets who are having an episode of low blood sugar and do not use pork insulins in pets with a pork allergy.

  • Dexamethasone is given on and off label, by mouth or injection, to treat various inflammatory, autoimmune, and adrenal gland conditions. It can also be used off label as a diagnostic test. Common side effects include increased drinking, urination and/or appetite, dull/dry haircoat, weight gain, pot-bellied appearance, muscle weakness, panting, vomiting, or diarrhea.

  • Prednisone/prednisolone is given by mouth or injection and is used on and off label to treat Addison’s disease, inflammatory conditions, neoplasia (cancer), and immune-mediated diseases. Give this medication as directed by your veterinarian.

  • Furosemide is given by mouth or injection and is used on and off label to treat many conditions, including congestive heart failure and fluid retention. Common side effects include increased urination, diarrhea, or constipation. Do not use in pets that are allergic to it or in those that are unable to make urine.

  • Propranolol (brand names Inderal®, Detensol®, Hemangeol®, Innopran®) is a beta-blocker used off label (extra label) to treat abnormal heart rhythms (arrhythmias) in cats, dogs, ferrets, and horses. It has also been used short-term to treat hypertension caused by thyrotoxicosis or pheochromocytoma. It is given by mouth or injection.

  • Triamcinolone acetonide topical (brand names Genesis®, Vetalog®, others) is a corticosteroid used to treat itching, skin irritation, and rashes in dogs. It may be specially compounded and/or combined into a formulation with other medications. It is used off label in other species. Triamcinolone topical comes in cream and spray forms.

  • Atenolol is used off label and given by mouth to treat certain heart conditions in dogs, cats, and ferrets. Common side effects include tiredness and stomach upset. Contraindications include hypersensitivity to beta-blockers, heart failure, heart block, low heart rate, or certain lung disease. If a negative reaction occurs, please call your veterinary office.