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Diabetes mellitus is an inability to regulate blood glucose caused by a loss of insulin production (Type I) or inadequate insulin supply or resistance (Type II). In cats, diabetes mellitus is most often type II. This type of diabetes usually results from obesity, creating insulin resistance. Cats with type II may be treated with oral medication, but some cats may ultimately require insulin injections. Diet is also important. This article discusses various treatments and monitoring regimens.
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Diabetes is an inability of the body to regulate blood sugar caused by an abnormality of the pancreas. It is the second-most common endocrine disease in cats. It causes increased thirst, urination, appetite, and weight loss. Cats most commonly have type 2 diabetes, caused by decreased insulin production or insulin resistance, and it is often associated with obesity. Diabetes is diagnosed by measuring increased levels of glucose in the urine and blood. Diabetes treatment includes insulin injections and dietary changes. Changes in blood sugar must be monitored regularly.
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Testing for diabetes includes confirming hyperglycemia and glucosuria while looking for other conditions by taking a complete blood count (anemia, infection), biochemistry profile (hepatic disease, pancreatitis), and a urinalysis (urinary tract infection). Monitoring includes regular glucose curves and additional exams and testing based on the pet owner's monitoring of their dog's clinical signs at home. Urine glucose testing and fructosamine are sometimes used in diabetic monitoring and urine testing for infection may be recommended.
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Diabetes is an inability of the body to regulate blood sugar caused by an abnormality of the pancreas. It causes increased thirst, urination, appetite, and weight loss. Most dogs have type 1 diabetes, caused by total or near destruction of the insulin-producing cells, and insulin injections are required for treatment. Diabetes is diagnosed by measuring increased levels of glucose in the urine and blood. Diabetes treatment includes insulin injections and dietary manipulation with regular blood sugar monitoring. Financial costs can be high during the regulation period, or if a complication arises, and twice-daily insulin injections are a lifelong commitment.
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Nutrition is very important in managing cats with diabetes mellitus. Achieving a lean body condition is associated with better glucose control and an increased chance of remission. Other factors in dietary management of diabetes mellitus are discussed.
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Testing for diabetes includes confirming hyperglycemia and glucosuria while looking for other conditions by taking a complete blood count (anemia, infection), biochemistry profile (hepatic disease, pancreatitis), and a urinalysis (urinary tract infection). Monitoring includes regular glucose curves and additional exams and testing based on the pet owner's monitoring of their cat's clinical signs at home. Urine glucose testing and fructosamine are sometimes used in diabetic monitoring and urine testing for infection may be recommended.
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Dogs usually have insulin-dependent diabetes (also called Type 1 diabetes), and require insulin injections to stabilize their blood sugar levels. This handout outlines the basics of treatment and monitoring, and also discusses the importance of diet.
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Diabetes mellitus is a disease in which the body can no longer appropriately manage glucose for its energy requirements. Overweight and obese dogs are at greater risk of developing DM, so obesity prevention should be started early in puppyhood, with portion-controlled meal feeding. Once a dog has been diagnosed with DM, an owner must work closely with their veterinarian to choose insulin therapy and an appropriate diet to achieve stable blood glucose (good glycemic control).
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Diabetes insipidus results in excessive drinking and urination. As many conditions cause these signs, a number of diagnostic tests including bloodwork and urinalysis need to be performed to rule out other causes. After more common causes are ruled out, a modified water deprivation test can confirm disease and an MRI or therapeutic trial can be performed. Diabetes insipidus results from reduced production of ADH from the brain or reduced sensitivity to ADH in the kidney. Treatment depends on the cause of the disease either replacing the lack of ADH with a synthetic replacement or using a hydrochlorothiazide and a low salt diet to decrease urine production.
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Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body's response to the injections needs to be regularly monitored using an at-home glucometer or continuous glucose monitoring system. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet.