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  • Chlorothiazide/hydrochlorothiazide is given by mouth or injection and is used off label to treat nephrogenic diabetes insipidus, high blood pressure, fluid retention, and certain electrolyte imbalances in dogs and cats. Give as directed by your veterinarian.

  • Urinalysis is an important part of any comprehensive workup or health screen. It provides information on the urinary system including the kidneys and bladder and also can support diagnosis of metabolic disease, such as diabetes mellitus.

  • Clinical signs of pituitary tumors depend on whether the tumor is functional or non-functional. Functional tumors can cause Cushing's disease in dogs and can cause acromegaly and insulin-resistant diabetes in cats. Non-functional pituitary tumors can enlarge to cause neurological signs. Diagnosis is based on the history, bloodwork, urinalysis, and sometimes a CT scan or MRI. Medical therapy is often the treatment of choice for functional tumors. Radiation therapy is another option and is usually the primary treatment for non-functional tumors.

  • The pancreas is an organ near the stomach and small intestine that produces enzymes needed for digestion, as well as hormones such as insulin that regulate blood sugar levels. Dogs with exocrine pancreatic insufficiency (EPI) are unable to digest nutrients in their diet properly, resulting in maldigestion, weight loss, and abnormal feces than can appear unusually pale and fatty. The disease can be congenital, genetic (such as in German shepherds), or acquired through pancreatic damage. Prognosis is good with treatment, although rarely diabetes is associated with the condition.

  • Medroxyprogesterone acetate is given by mouth or injection and is used off label to treat reproductive conditions, sexual behaviors, and certain types of dwarfism and alopecia. Give this medication as directed by your veterinarian. Common side effects include increased appetite, increased thirst, weight gain, sleepiness, or changes in personality. Do not use in pets that are allergic to it, pets with diabetes or uterine bleeding, or prior to puberty, during pregnancy, 1-2 months after a heat cycle, or to treat false-pregnancy. If a negative reaction occurs, please call your veterinary office.

  • Carpal hyperextension is an abnormality of the carpus (wrist) that causes increased extension of the joint. Carpal hyperextension in cats is typically caused by trauma. Cats can also develop carpal hyperextension in association with other systemic diseases (e.g., inflammatory arthritis, diabetes mellitus, electrolyte abnormalities). Cats with carpal hyperextension have a noticeable bend at the wrist, forcing their foot into an abnormally flattened position. If carpal hyperextension is caused by trauma, it may also be associated with pain and swelling. A tentative diagnosis of carpal hyperextension can be made based on initial observation, but a thorough physical examination is necessary because cats with carpal hyperextension may also have abnormalities in other joints. X-rays and other additional tests may be recommended. Treatment of carpal hyperextension depends upon the severity of the condition and may involve surgery.

  • Megestrol acetate is given by mouth in the form of a tablet or liquid and is used in dogs or off label in cats to postpone the heat cycle or to treat false pregnancy. It can also be used off label in male dogs to treat prostatic hypertrophy. It should not be used in pregnant pets or pets with uterine disease, diabetes, or breast tumors.

  • Obesity is the most common problem in dogs in North America and leads to an increased risk of diabetes mellitus, heart disease, and several types of cancer. Extra body fat causes increased inflammation associated with osteoarthritis. Reducing inflammation and pain can help an overweight dog to regain activity, which in turn can lead to more appropriate weight loss. Obesity can be prevented or reversed when dog owners are aware of calorie intake, body condition, and exercise.

  • Overweight cats have an increased risk of many health conditions, including diabetes, arthritis, high blood pressure, and some forms of cancer. This article reviews the components of a strong weight loss plan and includes tips for success to discourage begging and help promote healthy weight loss in cats who live in a multi-cat household.

  • Overweight dogs have an increased risk of many health conditions, including diabetes, arthritis, high blood pressure, and some forms of cancer. This article reviews the components of a strong weight loss plan and includes tips for success to discourage begging and help promote healthy weight loss in dogs who live in a multi-dog household.