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  • Bexagliflozin (brand name Bexacat®, Brenzavvy®) is an oral glycemic control medication used in cats with diabetes mellitus. It is used to lower blood sugar levels in cats with diabetes mellitus not previously treated with insulin. Bexagliflozin comes in tablet form.

  • Velagliflozin (brand name Senvelgo®) is an oral glycemic control medication used in cats with diabetes mellitus. It is used to lower blood sugar levels in cats with diabetes mellitus not previously treated with insulin. Velagliflozin comes in liquid suspension form.

  • Cushing's disease is a condition in which the adrenal glands over-produce certain hormones. It may be caused by a pituitary gland tumor, an adrenal tumor, or prolonged corticosteroid use. Clinical signs include poor haircoat, pot-bellied appearance, increased drinking, and increased urination. Medical and surgical treatment options are discussed. Prognosis varies but is improved with intervention.

  • Exenatide (brand names Bydureon®, Byetta®) is a glucagon-like peptide-1 (GLP-1) receptor agonist used in addition to insulin to achieve better blood sugar control and treat certain types of diabetes in cats. Its use is off label in veterinary medicine. Exenatide comes in an injectable immediate-release and extended-release forms – the forms are not interchangeable.

  • Insulin is injected under the skin to treat diabetes, ketoacidosis, and high potassium levels. Side effects may include low or high blood sugar levels, insulin resistance, and skin allergic reactions to the injections. Do not use in pets who are having an episode of low blood sugar and do not use pork insulins in pets with a pork allergy.

  • Glipizide is given by mouth and is used off label to treat high blood sugar in cats with mild type 2 diabetes. Give as directed by your veterinarian. Common side effects include temporary vomiting and a lack of appetite. Do not use in pets that are allergic to it or other sulfonamides, or in pets with trauma, infection, diabetic coma, low blood sugar, or diabetic ketoacidosis. If a negative reaction occurs, please call the veterinary office.

  • Cats with diabetes have the potential to go into remission where they may no longer need to receive insulin. Factors that can affect the likelihood of remission include the type of insulin given, your cat's diet, and how long your cat has been diabetic. It is important to recognize the signs of hypoglycemia, as they may be your first indication of remission.

  • Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The clinical signs depend on the type of macroadenoma, though become severe over time in either case. Diagnosis requires specialized CT or MRI imaging. This handout explains the effects of macroadenomas in cats and the treatment options available.

  • Inappropriate urination happens in well-trained pets for many reasons, including inflammation, infection, estrogen deficiency, kidney failure, diabetes mellitus, diabetes insipidus, Cushing's disease, neurological disease, or behavioral issues. A number of screening tests will be performed by your veterinarian to determine the root cause of the inappropriate urination. These tests are outlined in this article.

  • Certain medical conditions require drugs that are available only in an injectable format. In many cases, cat owners can administer these medications at home. Most cats do not mind routine injections that are given in the subcutaneous tissue. This handout provides step-by-step instructions for giving an injection. Dispose of used needles and syringes properly.